MRSA Gene Hunt
This is a classroom-based activity from the Wellcome Trust Sanger Institute that allows students to explore the features of two bacterial pathogen genomes. The aim of the activity is to highlight the role of different genetic components in two strains of Staphylococcus aureus and to identify how these have led to one strain becoming…
Build a Bug Activity
This is a classroom-based activity from the Wellcome Trust Sanger Institute that allows students to explore the features of two bacterial pathogen genomes. The aim of this activity is to highlight the role of different genetic components in two closely related subspecies of Salmonella enterica, and to identify how these contribute…
Malaria Challenge: Funding Decisions
From the Wellcome Trust Sanger Institute, this resource helps students to consider the allocations of funds to one or more malaria intervention projects. In groups they must discuss the pros and cons of different the projects and decide which should receive funding. Students can use the Malaria Challenge resource (also included…
Malaria Challenge: Big Debate
Produced by the Wellcome Trust Sanger Institute, these materials are designed to be used in conjunction with the Malaria Challenge materials (also included in this collection on the eLibrary). Students use the Malaria Challenge resource to research one of five different stages of the malaria cycle. In groups they discuss the…
Balloon Bugs
This resource from Wellcome Trust Sanger Institute is a practical, classroom activity that allows the students to make a balloon model of a disease-causing bacterium. This illustrates its basic shape and structure. Students can choose from three bacteria species including: 1. Salmonella Typhimurium and Campylobacter jejuni which…
Function Finders
Produced by the Wellcome Trust Sanger Institute, in this activity students translate DNA sequences into a series of amino acids to discover which protein is coded for and its function. Students are supplied with a worksheet with DNA sequences and a codon wheel to decode the codons into amino acids. The amino acid sequence can…
Model Organisms: Zebra Fish
Produced by the Wellcome Trust Sanger Institute, in this activity students have to use their observational skills to identify and record the difference (phenotypic change) between two images, one wild type zebra fish and one mutant zebra fish. To aid in their diagnosis of the phenotypic change, a glossary is provided to give…
KRAS: Cancer Mutation Activity
These materials contain a range of activities where students use real genomic data from the Cancer Genome Project at the Wellcome Trust Sanger Institute to find mutations in a gene associated with pancreatic cancer. Students mark the locations of the mutations on a gene sequence banner and record the results on worksheets. The…