Paracetamol

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This book from the Royal Society of Chemistry consists of seven free-standing activities that can be used singly or as a coherent package in a wide range of teaching and learning situations in both academic and vocational courses. It is aimed at post-16 chemistry students and their teachers.

The book is organised into two main sections - a series of student activities and a guide for teachers and technicians with equipment lists and answers. Within the section for students there are both written and practical tasks. The practical tasks are both preparative/analytical and problem solving.

Contents
• Background information
• Paracetamol is a common compound
• The history of paracetamol
• Experimental and investigation section
• The extraction and purification of paracetamol from tablets
• Paracetamol form u I at ions : presentation activity
• The preparation of paracetamol
• Step 1 .the nitration of phenol
• Step 2 .the reduction of a nitro group to an amine
• Step 3 .the formation of an amide
• The quantitative analysis of various formulations of paracetamol
• Teachers’ notes
• Using thin-layer chromatography to investigate the reactions
• The toxicity of paracetamol
• Apparatus lists and answers

URL: http://stem.org.uk/rx72d

HEALTH and SAFETY
Any use of a resource that includes a practical activity must include a risk assessment. Please note that collections may contain ARCHIVE resources, which were developed at a much earlier date. Since that time there have been significant changes in the rules and guidance affecting laboratory practical work. Further information is provided in our Health and Safety guidance.