Chemistry Now – Combinatorial Chemistry
This leaflet is part of the Royal Society of Chemistry’s series called Chemistry Now. The leaflet consists of four pages of information interspersed with questions to test student’s understanding of what they are reading, to help them to link what they have read to the chemistry they already know and to help them to understand the text. The leaflets could be used to support existing workschemes, to develop comprehension skills or as meaningful exercises to be used in the case of teacher absences (planned or unplanned).
This leaflet is aimed at the post-16 age group. Combinatorial chemistry is a group of techniques for synthesising large arrays of related chemicals. These can be easily automated by the use of robot syringes controlled by computers to carry out repetitive processes. The resulting arrays of chemicals called ‘libraries’ can then be screened for potential drug activities. Combinatorial chemistry is increasingly being used by pharmaceutical companies in their search for new drugs.
HEALTH and SAFETY
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